Evidence / Study 02

MCAO treatment window.

A timeline for the source-reported 2 h, 6 h and 24 h treatment-window narrative.

Conceptual neurovascular scientific plate related to this page
03 / evidence

The band shows temporal narrative, not a fabricated efficacy axis.

preclinicalMiddle cerebral artery occlusion (MCAO)preclinical_in_vivosource_mapped

Research question

Describe the source-reported acute treatment-window narrative in an MCAO model.

Methods

ModelMCAO
SpeciesRat
InterventionAildenafil phosphate
DoseNot specified in current source
Timing2 h, 6 h and 24 h after the source-described event
ComparatorNot specified in the current source summary
  • The current source map describes the timepoints and a functional narrative, but not a numerical efficacy series.

Source results

Source result table
EndpointTimepointSource result
Investigated treatment timepoint2 h2 h is one of the source-reported treatment timepoints described as having a favorable effect narrative.
Investigated treatment timepoint6 h6 h is one of the source-reported treatment timepoints described as having a favorable effect narrative.
Investigated treatment timepoint24 h24 h is one of the source-reported treatment timepoints described as having a favorable effect narrative.
Motor-function contextimprovement described in the source summary
FIG. 02Observed events · temporal lineage

The source narrative spans 2, 6 and 24 h—without an efficacy scale.

Three lineages start at the MCAO model event and terminate at source-reported administration times; line length encodes time only.
Administration-event lineages after MCAO Three vertical lineages extend from the MCAO model event to source-reported administration at 2, 6 and 24 hours.hours after MCAO0 h2 h6 h12 h18 h24 hT+02source administrationmodel eventT+06source administrationT+24source administrationno effect-size encoding

Interpretation

The figure communicates the source-reported window narrative, not a ranked efficacy curve.

Limitations

  • No numerical motor-function scores, comparator values or statistical outputs are mapped in the current source summary.